In this work, the study of interaction of alpha and proton particles of CeF₃ doped tungsten borate glass system were studied and were compared with Gd₂O₃ doped tungsten borate glass. The mass stopping power, projected range and the simulation of alpha particles and proton particles were calculated using SRIM program. From the results, when shoot alpha particles with  and protons particles with , the mass stopping power and projected range of CeF₃-doped tungsten borate glass were higher than those of that Gd₂O₃-doped tungsten borate glass. From the simulation of alpha particles and proton particles passing through the material at 1 μm of thickness, with energy of 50 keV. The results showed that CeF₃-doped tungsten borate glass has more particles through the material than Gd₂O₃-doped tungsten borate glass. In other words, Gd₂O₃-doped tungsten borate glass can inhibit alpha and proton particles from entering the material better than CeF₃-doped tungsten borate glass. Therefore, Gd₂O₃-doped tungsten-borate glass had better inhibition of alpha particles and protons than CeF3-doped tungsten-borate glass.