This article presents a cross-sectional study to study the prevalence of the abnormalities of the musculoskeletal system of the computer group students. Nakhon Pathom Rajabhat University and to determine factors that correlate with disorders of the skeletal musculoskeletal system of computer students Nakhon Pathom Rajabhat University age range 19-23 years on 300 people in this study questionnaires were used to collect data and analyzed with descriptive statistics. Using the musculoskeletal abnormalities assessment form. Based on the Nordic Questionnaire and the Rapid Office Strain Assessment (ROSA) computer risk assessment form by statistical method with SPSS program. The research consisted of percentage, frequency, mean and standard deviation. using chi-square analysis. The results were as follows (1) the prevalence of disorders of the musculoskeletal system using the Nordic Questionnaire. It was found that the students in the computer field with disorders of the musculoskeletal system It asked about pain in 12 different parts of the body during 7 days and 12 months. It was found that the neck was the most abnormal organ of the musculoskeletal system. accounted for 70.7 and 87.0 percent, respectively. In addition, other abnormalities of the musculoskeletal system were found in the 7-day cycle, including the upper back. The lower back area during the 12-month period includes the lower back area. upper back area and other parts of the body which said that computer students Aches and pains can be found from all parts of the body. from sitting at the computer for a long time (2) The relationship between personal factors and work factors found that in 7 days, BMI, time spent using computers in the classroom, time spent using computers at work or House It is associated with disorders of the musculoskeletal system. at 0.05 level of statistical significance, gender, age, physical activity duration of admission How long does the computer use for playing games and other activities such as researching information on the website There were no abnormalities in the musculoskeletal system. In 12 months, gender, BMI, time spent using computers in the classroom, time spent using computers at work, or Home is associated with disorders of the musculoskeletal system. at 0.05 level of statistical significance, age, exercise duration of admission How long does the computer use for playing games? and other activities such as researching information on the website It was not associated with musculoskeletal disorders.