The objective of this study was to study attitudes towards vaccination against COVID-19 of students of the Faculty of Nursing Rambhai Barni Rajabhat University. The target population is nursing students faculty of Nursing 150 students, Rambhai Barni Rajabhat University, 1st - 3rd year. Simple random sampling using tables of Krejcie & Morgan (1970). The sample group consisted of 109 people. Inclusive criteria was a  happy to provide information. The questionnaire are students' attitudes towards COVID-19 and the attitude assessment form of students towards vaccination against COVID-19, using an online test response. The data were analyzed using statistics, percentage, mean (X), and standard deviation (SD). It was found that the assessment of students' attitudes towards COVID-19 was at a good level (X = 3.69), when classified by the highest aspect was social aspect. The mean was at good level (mean 4.06), followed by physical aspect, mean was good (X=3.83) and mental aspect, mean was moderate (X=3.17), respectively. Students continue to vaccinate against COVID-19 The mean was moderate (X = 3.30) when classified by the highest aspect was information about vaccines. The mean was in good level (X = 3.44), followed by vaccine efficacy. The mean was at a moderate level (X=3.36) in terms of satisfaction with vaccination. The mean was moderate (X=3.24) and the safety of vaccines. The mean was moderate (X=3.15), respectively.